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盐酸酚苄明
Phenoxybenzamine Hydrochloride
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3180986 | 1 G | 965 |
产品别名
63-92-3
盐酸酚苄明
Phenoxybenzamine Hydrochloride
N-(2-Chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzylamine hydrochloride
盐酸酚苄明 盐酸盐
N-(2-氯乙基)-N-(1-甲基-2-苯氧乙基)苄胺 盐酸盐
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C18H22ClNO · HCl |
Molecular weight | 340.29 |
EC number【EC 号】 | 200-569-7 |
MDL number | MFCD00055152 |
PubChem Substance ID【PubChem化学物质编号】 | 329823375 |
NACRES | NA.24 |
General description【一般描述】 | Phenoxybenzamine Hydrochloride is an important drug belonging to the class of β-chloroethylamine drugs. It functions as an α-blocker by binding to α-adrenoreceptors, located on vascular smooth muscles and stops the influence of sympathetic nerves on blood vessels. It is widely used in the treatment of hypertension, benign prostatic hyperplasia and hypoplastic left heart syndrome. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
Application【应用】 | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Phenoxybenzamine Hydrochloride may be used as a pharmaceutical reference standard in the determination of the analyte in pharmaceutical formulations by chromatographic and chemiluminescence techniques. |
Biochem/physiol Actions【生化/生理作用】 | 钙调蛋白拮抗剂;α-肾上腺素受体拮抗剂。 |
Analysis Note【分析说明】 | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
Other Notes【其他说明】 | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
Footnote【附注】 | To see an example of a Certificate of Analysis for this material enter LRAA2196 in the slot below. This is an example certificate only and may not be the lot that you receive. |
产品性质
Quality Level【质量水平】 | 300 |
grade【等级】 | certified reference material pharmaceutical secondary standard |
CofA | current certificate can be downloaded |
technique(s) | HPLC: suitable gas chromatography (GC): suitable |
application(s) | pharmaceutical (small molecule) |
format【格式】 | neat |
pharmacopeia traceability【药典可追溯性】 | traceable to USP 1526007 |
storage temp.【储存温度】 | 2-30℃ |
SMILES string | Cl[H].CC(COc1ccccc1)N(CCCl)Cc2ccccc2 |
InChI | 1S/C18H22ClNO.ClH/c1-16(15-21-18-10-6-3-7-11-18)20(13-12-19)14-17-8-4-2-5-9-17;/h2-11,16H,12-15H2,1H3;1H |
InChI key | VBCPVIWPDJVHAN-UHFFFAOYSA-N |
Gene Information | human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152) |
安全信息
Pictograms【象形图】 | GHS07,GHS08 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H302 - H351 |
Precautionary Statements | P201 - P301 + P312 + P330 - P308 + P313 |
Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Carc. 2 |
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |