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palmitic-acid-9-hydroxy-stearic-acid
产品别名
palmitic-acid-9-hydroxy-stearic-acid
9-PAHSA
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C34H66O4 |
Molecular weight | 538.89 |
PubChem Substance ID【PubChem化学物质编号】 | 329768748 |
NACRES | NA.22 |
General description【一般描述】 | Palmitic-acid-9-hydroxy-stearic-acid (9-PAHSA) is an isomeric form of bioactive fatty acid ester of hydroxyl-fatty acid (FAHFA). |
Application【应用】 | 9-PAHSA is composed of palmitic acid attached to stearic acid and is in the class of branched lipids referred to as fatty acid esters of hydroxy fatty acids (FAHFAs). 9-PAHSA was found at increased levels in serum and white adipose tissue of insulin-sensitive mice. Levels were found to be lower in white adipose tissue of insulin-resistant humans. Studies of oral administration of 9-PAHSA to obese, diabetic mice showed improved glucose tolerance. In characterizing the mechanism, it was found that 9-PAHSA stimulates insulin and GLP-1 secretion and also enhances glucose transport and the Glut4 transporter through activation of GPR-120. 9-PAHSA was also shown to have anti-inflammatory properties. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | 95% |
form【形式】 | solid |
mp | 33.5 ℃ |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | CCCCCCCCCC(OC(CCCCCCCCCCCCCCC)=O)CCCCCCCC(O)=O |
InChI | 1S/C34H66O4/c1-3-5-7-9-11-12-13-14-15-16-18-23-27-31-34(37)38-32(28-24-20-17-10-8-6-4-2)29-25-21-19-22-26-30-33(35)36/h32H,3-31H2,1-2H3,(H,35,36) |
InChI key | MHQWHZLXDBVXML-UHFFFAOYSA-N |
packaging【包装】 | 250 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |