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产品别名
3308-62-1
p30
结构式
基本信息
| MDL number | MFCD01727216 |
| PubChem Substance ID【PubChem化学物质编号】 | 329820082 |
| NACRES | NA.54 |
| Application【应用】 | p30 is an endogenous truncated form of p39 that associates with Cdk5 to form Nclk, which regulates neurotransmission, axon guidance, central nervous system (CNS) architecture, and pathogenesis. Therefore, p30 is useful in studying neurodegenerative diseases such as Alzheimer′s, Amyotrophic Lateral Sclerosis, and Parkinson′s Disease. |
| Biochem/physiol Actions【生化/生理作用】 | P30 activates GST-Neuronal cyclin-dependent kinase 5 (Cdk5). It also associates with Cdk5 to form an activated neuronal Cdc2-like kinase (Nclk). Product P1246 is recombinant, from bovine and is expressed in E. coli. |
| Unit Definition【单位定义】 | One unit will incorporate 1 picomole of phosphate into histone H1 peptide per minute at pH 7.2 at 30 ℃. |
| Physical form【外形】 | p30 is supplied in a solution of 25 mM Tris, pH 7.4, 1 mM DTT, and 30% glycerol. (0.5 μg protein/ 25 ul vial) |
| Preparation Note【制备说明】 | Expressed as a GST fusion protein. |
产品性质
| Quality Level【质量水平】 | 200 |
| form【形式】 | solution |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | Cl.CN(C)CCOc1ccc2OCCOc2c1 |
| InChI | 1S/C12H17NO3.ClH/c1-13(2)5-6-14-10-3-4-11-12(9-10)16-8-7-15-11;/h3-4,9H,5-8H2,1-2H3;1H |
| InChI key | VRCSNYKNBODDIM-UHFFFAOYSA-N |
