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Nimodipine
产品编号:3175166
规格:Pharmaceutical Secondary Standard; Certified Reference Material
CAS NO:66085-59-4
包装规格:1 G
产品类别:进口试剂
品牌:Supelco
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
31751661 G1480
产品别名

66085-59-4

尼莫地平

Nimodipine

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl 1-methylethyl ester

Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate

1,4-二氢-2,6-二甲基-4-(3-硝基苯基)-3,5-吡啶二甲酸-2-甲氧基乙基1-甲基乙基酯

1,4-二氢-2,6-二甲基-4-(间硝基苯基)-3,5-吡啶二甲酸异丙酯-2-甲氧基乙酯

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C21H26N2O7
Molecular weight
418.44
EC number【EC 号】
266-127-0
MDL number
MFCD00153848
PubChem Substance ID【PubChem化学物质编号】
329823284
NACRES
NA.24
General description【一般描述】
Nimodipine is a well-known calcium antagonist and is a moderate cerebral vasodilator, in addition to being an inhibitor of cerebrovascular reactivity. It is suggested to be cytoprotective by causing a decrease in the influx of calcium into the nerve cells. It is accepted for use in the management of delayed ischaemic dysfunction and is commonlly used in the studies of brain function impairment and dementia in old age.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Application【应用】
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Nimodipine can be used as a pharmaceutical reference standard in the determination of the analyte in pharmaceutical formulations and combined dosage forms by various electrochemical and spectrophotometric techniques.
Analysis Note【分析说明】
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Other Notes【其他说明】
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote【附注】
To see an example of a Certificate of Analysis for this material enter LRAA0583 in the slot below. This is an example certificate only and may not be the lot that you receive.
产品性质
Quality Level【质量水平】
300
grade【等级】
certified reference material
pharmaceutical secondary standard
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format【格式】
neat
pharmacopeia traceability【药典可追溯性】
traceable to BP 651
traceable to PhEur N0850000
traceable to USP 1463858
storage temp.【储存温度】
2-8℃
SMILES string
COCCOC(=O)C1=C(C)NC(C)=C(C1c2cccc(c2)[N+]([O-])=O)C(=O)OC(C)C
InChI
1S/C21H26N2O7/c1-12(2)30-21(25)18-14(4)22-13(3)17(20(24)29-10-9-28-5)19(18)15-7-6-8-16(11-15)23(26)27/h6-8,11-12,19,22H,9-10H2,1-5H3
InChI key
UIAGMCDKSXEBJQ-UHFFFAOYSA-N
Gene Information
human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779), NR3C2(4306)
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H302
Precautionary Statements
P264 - P270 - P301 + P312 - P501
Hazard Classifications【危险分类】
Acute Tox. 4 Oral
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 1
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