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烟酸

Nicotinic Acid
产品编号:3175061
规格:meets USP testing specifications
CAS NO:59-67-6
包装规格:100 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
3175061100 G3340
产品别名

59-67-6

烟酸

Nicotinic Acid

Pellagra preventive factor

Niacin

Pyridine-3-carboxylic Acid

Vitamin B3

3-Picolinic acid

尼亚生

抗糙皮病因子

维生素 B3

3-吡啶甲酸

吡啶-3-羧酸

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C6H5NO2
Molecular weight
123.11
Beilstein
109591
EC number【EC 号】
200-441-0
MDL number
MFCD00006391
PubChem Substance ID【PubChem化学物质编号】
24897734
NACRES
NA.21
General description【一般描述】
Nicotinic acid, also referred to as niacin or as vitamin B3, is a water-soluble vitamin. Nicotinic acid is synthesized from the amino acid tryptophan and is present majorly in peanuts, fish and lean meat.
Application【应用】
Nicotinic acid has been used as an antioxidant to evaluate its protective functionality in colon LoVo cell lines against doxorubicin induced cytotoxicity.
Biochem/physiol Actions【生化/生理作用】
Nicotinic modulates lipid metabolism and may be useful in treating dyslipidemia. It is an antioxidant and acts as a coenzyme in the form of nicotinamide adenine nucleotides. Deficiency of niacin leads to enhanced lipid peroxidation and is also implicated in Crohn′s disease Deficiency also impacts DNA repair and also leads to skin and gastrointestinal disorder, pellagra. Nicotinic acid reduces the low-density lipoprotein (LDL) synthesis and improves high-density lipoprotein (HDL) levels.
产品性质
Quality Level【质量水平】
200
biological source【生物来源】
synthetic (organic)
agency
USP/NF
meets USP testing specifications
Assay【测定】
99.0-101.0% dry basis
form【形式】
powder
color【颜色】
white
mp
236-239 ℃ (lit.)
application(s)
pharmaceutical (small molecule)
SMILES string
OC(=O)c1cccnc1
InChI
1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)
InChI key
PVNIIMVLHYAWGP-UHFFFAOYSA-N
Gene Information
human ... CYP1A2(1544)
rat ... Chrnb2(54239)
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H319
Precautionary Statements
P280 - P305 + P351 + P338 - P337 + P313
Hazard Classifications【危险分类】
Eye Irrit. 2
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 1
Flash Point(F)【闪点(F)】
379.4 °F - closed cup
Flash Point(C)【闪点(C)】
193 ℃ - closed cup
Personal Protective Equipment【个人防护装备】
dust mask type N95 (US), Eyeshields, Gloves
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