Anti-TOM22 antibody , Mouse monoclonal

MFCD03457578

NA.41

Translocase of outer mitochondrial membrane 22 (TOMM22) is an essential receptor of the mitochondrial import channel. It is characterized with an N-terminal negatively charged region exposed to the cytosol, a putative transmembrane region and a C-terminal intermembrane space region with little negative charge.

membrane fraction from Vero (monkey kidney-derived) cells.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

• Western blotting

Translocase of outer mitochondrial membrane 22 (TOMM22) is a key constituent of TOM complex. It functions as a mitochondrial receptor for the proapoptotic protein Bax (BCL2-associated X protein). TOMM22 interacts with 3-β hydroxysteroid dehydrogenase 2 (3βHSD2) and converts pregnenolone-to-progesterone in steroidogenic cells.

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% BSA and 15 mM sodium azide.

200

mouse

unconjugated

purified from hybridoma cell culture

primary antibodies

1C9-2, monoclonal

buffered aqueous solution

antigen 22 kDa

human, monkey

rodent

~1 mg/mL

immunocytochemistry: suitable
microarray: suitable
western blot: 0.5-1.0 μg/mL using whole extract of cultured human lymphoma Raji cells.

IgG1

Q9NS69

dry ice

−20℃

human ... TOMM22(56993)

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12 - Non Combustible Liquids

WGK 3