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Anti-TES antibody ,Mouse monoclonal

产品编号:3153385
规格:clone TES75, purified from hybridoma cell culture
包装规格:200 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3153385200 μL5700
产品别名

Anti-TES antibody ,Mouse monoclonal

Anti-TESTIN

Anti-TESS-2

Anti-Testis derived transcript

Anti-TESS

基本信息
NACRES
NA.41
General description【一般描述】
Monoclonal Anti-TES (mouse IgG3 isotype) is derived from the hybridoma TES75 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide. Testin LIM domain protein (TES) comprises cysteine-rich zinc-binding motifs called LIM domains and is a component of focal adhesions. TES gene is mapped to a common fragile site on chromosome 7q31.2 is designated as FRA7G.
Specificity【特异性】
Monoclonal Anti-TES recognizes human, monkey, bovine, and mouse TES
Application【应用】
Anti-TES antibody, mouse monoclonal may be used in immunoblotting.
Biochem/physiol Actions【生化/生理作用】
Testin LIM domain protein (TES), a putative tumor-suppressor gene, is essential for motility and is key for the tumor cell anchorage and metastasis. TES mRNA expression is found in several cancer-derived cell lines, particularly hematopoietic, breast and ovarian cancer cell lines as well as in primary tumors. This was correlated with methylation of TES CpG island. Furthermore, TES gene knockout revealed its role as a tumor suppressor gene as well as in actin stress fibre organization.
Physical form【外形】
0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。
产品性质
Quality Level【质量水平】
200
biological source【生物来源】
mouse
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
purified from hybridoma cell culture
antibody product type
primary antibodies
clone【克隆】
TES75, monoclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
antigen ~48 kDa
species reactivity
mouse, human, bovine, monkey
packaging【包装】
antibody small pack of 25 μL
concentration【浓度】
~1.5 mg/mL
technique(s)
western blot: 0.5-1.0 μg/mL using whole extract of mouse thymus
isotype【同位素/亚型】
IgG3
UniProt accession no.【UniProt登记号】
Q9UGI8
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... TES(26136)
mouse ... Tes(21753)
产品说明
Storage and Stability【储存及稳定性】
Store at –20 ℃. For continuous use, the product may be stored at 2–8 ℃ for up to one month. For extended storage, freeze at –20 ℃ in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
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