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Monoclonal Anti-STAT6 antibody produced in mouse

产品编号:3152762
规格:clone 4G7, purified immunoglobulin, buffered aqueous solution
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3152762100 μG5040
产品别名

Monoclonal Anti-STAT6 antibody produced in mouse

IL-4-STAT

D12S1644

STAT6B

STAT6C

产品性质
biological source【生物来源】
mouse
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
purified immunoglobulin
antibody product type
primary antibodies
clone【克隆】
4G7, monoclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
antigen ~38.1 kDa
species reactivity
human
technique(s)
capture ELISA: suitable
immunofluorescence: suitable
indirect ELISA: suitable
western blot: 1-5 μg/mL
isotype【同位素/亚型】
IgG2aκ
NCBI accession no.【NCBI登记号】
NM_003153
UniProt accession no.【UniProt登记号】
P42226
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... STAT6(6778)
基本信息
General description【一般描述】
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. (provided by RefSeq)
Immunogen【免疫原】
STAT6 (NP_003144, 694 a.a. ~ 801 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
PPHSHSIPPYQGLSPEESVNVLSAFQEPHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAFPQGTWIGEDIFPPLLPPTEQD
Physical form【外形】
Solution in phosphate buffered saline, pH 7.4
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 1
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