Monoclonal Anti-NF-κB antibody produced in mouse

MFCD00802846

NA.41

Nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 (NFKB1) is a subunit of nuclear factor κB (NF-κB) and exists as a dimer. It is expressed in the cytosol.
Monoclonal Anti-NF-κB p65 (mouse IgG1 isotype) is derived from the NF-12 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with a recombinant, mouse NF-κB p65 fragment. Nuclear factor κB (NF-κB1) is a member of NF-κB/Rel family of transcription factors.

recombinant mouse NF-κB p65 fragment (C-terminal, 151 amino acids).

Monoclonal Anti-NF-κB antibody produced in mouse has been used in immunohistochemistry and Western blotting.

Nuclear factor kappa-B (NF-κB1) has an ability to affect transcription of κB reporter genes positively or negatively when assayed following transfection.
Nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 (NFKB1) has a role in hippocampal neurogenesis. It regulates the signaling by nuclear factor κB (NF-κB). Deletion of the gene in mice leads to defects in innate and adaptive immunity. The protein acts as a mediator of apoptotic response to S-phase DNA damage and replication stress. NFKB1 modulates the structural plasticity of cortical neurons. Knockout of the protein in mice has been shown to cause liver apoptosis and embryonic death.

200

mouse

unconjugated

ascites fluid

primary antibodies

NF-12, monoclonal

antigen 65 kDa

15 mM sodium azide

human, mouse

immunocytochemistry: suitable
microarray: suitable
western blot: 1:1,000 using a whole cell extract from a mouse fibroblast cell line

IgG1

P19838

dry ice

−20℃

human ... NFKB1(4790)
mouse ... Nfkb1(18033)

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12 - Non Combustible Liquids

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