Monoclonal Anti-Na⁺/Ca²⁺ Exchanger antibody produced in mouse

MFCD01865491

NA.41

Na⁺/Ca²⁺ exchanger is also known as solute carrier family 8 member A1 (SLC8A1) and is present in the plasma membrane. It is predicted to have nine transmembrane segments and the gene encoding SLC8A1 has three promoters.

The antibody reacts specifically with Na⁺/Ca²⁺ exchanger in kidney and cardiac tissues. By immunohistology, staining of the plasma membrane and intense staining of the cardiac T-tubular membrane is observed. The antibody is not recommended for immunoblotting of rat tissues.

dog cardiac Na⁺/Ca²⁺ exchanger. The epitope is in the region of amino acids 371-525, which is on the intracellular side of the plasma membrane.

Na⁺/Ca²⁺ exchanger (SLC8A1, solute carrier family 8 member A1) is involved in Ca²⁺ homeostasis. Depending on physiological conditions prevailing in the cell, it can either pump out Na⁺ or Ca²⁺.

Solution in phosphate buffered saline, 1 mg/ml BSA containing 0.05% sodium azide.

200

mouse

unconjugated

primary antibodies

C2C12, monoclonal

liquid

antigen 120 kDa (mature exchanger)
antigen 160 kDa (non-reduced)
antigen 70 kDa (proteolytic fragment)

canine, rat, guinea pig, human, rabbit

immunohistochemistry (frozen sections): 1:200
immunoprecipitation (IP): suitable
western blot: 1:1,000

IgM

P32418

dry ice

−20℃

human ... SLC8A1(6546)

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Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)