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Monoclonal Anti-MAPK14, (C-terminal) antibody produced in mouse

产品编号:3148184
规格:clone 3D5, ascites fluid
包装规格:200 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3148184200 μL5040
产品别名

Monoclonal Anti-MAPK14, (C-terminal) antibody produced in mouse

Mxi2

PRKM14

CSBP2

EXIP

PRKM15

SAPK2A

RK

CSPB1

CSBP1

基本信息
NACRES
NA.41
General description【一般描述】
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. (provided by RefSeq)
Immunogen【免疫原】
MAPK14 (AAH31574, 260 a.a. ~ 360 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
QSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
Physical form【外形】
Clear solution
产品性质
biological source【生物来源】
mouse
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
ascites fluid
antibody product type
primary antibodies
clone【克隆】
3D5, monoclonal
mol wt【分子量】
antigen ~37.11 kDa
species reactivity
human
technique(s)
indirect ELISA: suitable
western blot: 1:500-1:1000
isotype【同位素/亚型】
IgG1κ
NCBI accession no.【NCBI登记号】
BC031574
UniProt accession no.【UniProt登记号】
Q16539
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... MAPK14(1432)
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 1
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