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Monoclonal Anti-KIRREL3, (C-terminal) antibody produced in mouse
| 产品编号： | 3147390 |
| 规格： | clone 3A12, purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Monoclonal Anti-KIRREL3, (C-terminal) antibody produced in mouse
KIAA1867
MGC126850
KIRRE
PRO4502
MGC126824
NEPH2
产品性质
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 3A12, monoclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~37.11 kDa |
| species reactivity | human |
| technique(s) | indirect ELISA: suitable western blot: 1-5 μg/mL |
| isotype【同位素/亚型】 | IgG2aκ |
| NCBI accession no.【NCBI登记号】 | NM_032531 |
| UniProt accession no.【UniProt登记号】 | Q8IZU9 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... KIRREL3(84623) |
基本信息
| General description【一般描述】 | The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. Mutations in this gene are associated with mental retardation autosomal dominant type 4 (MRD4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene |
| Immunogen【免疫原】 | KIRREL3 (NP_115920.1, 679 a.a. ~ 778 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence YSTLSGQGRLYDYGQRFVLGMGSSSIELCEREFQRGSLSDSSSFLDTQCDSSVSSSGKQDGYVQFDKASKASASSSHHSQSSSQNSDPSRPLQRRMQTHV |
| Physical form【外形】 | Solution in phosphate buffered saline, pH 7.4 |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
