Monoclonal Anti-Interferon-γ antibody produced in mouse

MFCD00162308

NA.41

recombinant human interferon-γ, expressed and purified from Escherichia coli.

Interferons (IFNs) are cytokines that are secreted in response to viral or bacterial infections and tumorigenesis. IFN-γ binds to specific receptor complex consisting of IFNγR1 and IFNγR2. There are many pathways that are mediated by IFN-γ binding such as JAK/STAT1, AP-1, NF-κB, STAT3 and STAT5. IFN-γ is pleotropic and performs various functions related to immune response, inflammation, differentiation and activation of T cells, cell cycle and apoptosis.

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5% trehalose.

Purified using protein A affinity chromatography.

100

mouse

unconjugated

purified immunoglobulin

primary antibodies

25718, monoclonal

lyophilized powder

human

immunocytochemistry: 8-25 μg/mL using immersion fixed human peripheral blood mononuclear cells stimulated with PMA and ionomycin
neutralization: suitable

endotoxin, tested

IgG2a

P01579

−20℃

human ... IFNG(3458)

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

13 - Non Combustible Solids

WGK 2

Eyeshields, Gloves, type N95 (US)