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抗-胰岛素样生长因子-I单克隆抗体 仓鼠抗
Monoclonal Anti-Insulin-like Growth Factor-I antibody produced in hamster
| 产品编号： | 3147024 |
| 规格： | clone 126002, purified immunoglobulin, lyophilized powder |
| 包装规格： | 500 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
抗-胰岛素样生长因子-I单克隆抗体 仓鼠抗
Monoclonal Anti-Insulin-like Growth Factor-I antibody produced in hamster
Anti-IGF-I
基本信息
| MDL number | MFCD00162566 |
| NACRES | NA.41 |
| General description【一般描述】 | Insulin-like Growth Factor-I (also known as somatomedinC and somatomedin A) and insulin-like growth factor-II(IGF-II) belong to the family of insulin-like growthfactors, which are structurally homologous to proinsulin.Mature IGF-I and IGF-II are h |
| Immunogen【免疫原】 | purified, E. coli-derived recombinant mouse insulin-like growth factor-I. |
| Biochem/physiol Actions【生化/生理作用】 | Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades. The effects of IGF-1R signaling are important at many developmental levels from cells to organ to organism, growth, differentiation, anti-apoptosis, proliferation and transformation. |
| Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | hamster |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 126002, monoclonal |
| form【形式】 | lyophilized powder |
| species reactivity | mouse |
| technique(s) | capture ELISA: 2-8 μg/mL neutralization: suitable western blot: 1-2 μg/mL |
| isotype【同位素/亚型】 | IgG1 |
| UniProt accession no.【UniProt登记号】 | P05017 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... Igf1(16000) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
