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Anti-hnRNP-A2/B1 antibody, Mouse monoclonal antibody produced in mouse
| 产品编号： | 3146499 |
| 规格： | clone DP3B3, purified from hybridoma cell culture |
| 包装规格： | 200 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-hnRNP-A2/B1 antibody, Mouse monoclonal antibody produced in mouse
Anti-Heterogeneous Nuclear Ribonucleoprotein-A2/B1
基本信息
| MDL number | MFCD03845440 |
| NACRES | NA.41 |
| General description【一般描述】 | Monoclonal Anti-hnRNP-A2/B1 (mouse IgG2a isotype) is derived from the DP3B3 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with recombinant human hnRNP-A2. hnRNP-A2/B1 proteins are located in the nucleus of most tissues cells. However, the hnRNP-A2 protein is found also in the cytoplasm of skin and esophagus cells. In rat brain, hnRNP-A2/B1 proteins are found in neurons in the cerebral cortices, hippocampal formation, olfactory regions, caudate-putamin and the supraoptic nucleus of the hypothalamus. |
| Immunogen【免疫原】 | recombinant human hnRNP-A2. |
| Application【应用】 | Monoclonal Anti-hnRNP-A2/B1 antibody produced in mouse been used in :
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| Biochem/physiol Actions【生化/生理作用】 | In cells, it actively participates in pre-messenger RNA (pre-mRNA) processing, mRNA metabolism and transportation. It is overexpressed in the initial stage of lung cancer and in premalignant lesions. It also participates in neurodegeneration mediated by rCGG (repeats). |
| Physical form【外形】 | Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide. |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | DP3B3, monoclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~36 kDa |
| species reactivity | rat, hamster, mouse, human, canine, chicken, monkey, bovine |
| technique(s) | immunocytochemistry: suitable immunoprecipitation (IP): suitable microarray: suitable western blot: 1-2 μg/mL using total cell extract from 293T cell line |
| isotype【同位素/亚型】 | IgG2a |
| UniProt accession no.【UniProt登记号】 | P22626 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... HNRNPA2B1(3181) mouse ... Hnrnpa2b1(53379) rat ... Hnrnpa2b1(362361) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
