Monoclonal Anti-GRLF1 antibody produced in mouse

MFCD07370425

NA.41

The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. (provided by RefSeq)

GRLF1 (AAH03514, 1 a.a. ~ 36 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MEATSRSVHGDVGEVGHFEGMAVCWCPRRGILPGLR

Solution in phosphate buffered saline, pH 7.4

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100

mouse

unconjugated

purified immunoglobulin

primary antibodies

4D4-F8, monoclonal

buffered aqueous solution

human

indirect ELISA: suitable

IgG2aκ

BC003514

dry ice

−20℃

human ... GRLF1(2909)

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12 - Non Combustible Liquids

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)