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Monoclonal Anti-FOXP3 antibody produced in mouse

产品编号:3145252
规格:clone 2A11G9, ascites fluid
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3145252100 μL5040
产品别名

Monoclonal Anti-FOXP3 antibody produced in mouse

XPID

PIDX

AIID

IPEX

JM2

基本信息
NACRES
NA.41
General description【一般描述】
Forkhead box P3 (FOXP3) is located on human chromosome Xp11.23-Xq13.3. FOXP3 is a putative DNA-binding protein and is a member of the forkhead family. The protein is mainly expressed in the CD4+CD25+ regulatory T-cell subsets.
Immunogen【免疫原】
Purified recombinant fragment of human Foxp3 expressed in E.coli.
Mouse monoclonal antibody raised against Foxp3
Application【应用】
Monoclonal Anti-FOXP3 antibody has been used in immunohistochemistry (IHC).
Biochem/physiol Actions【生化/生理作用】
Forkhead box P3 (FOXP3) plays an essential role in the development of CD4+CD25+ regulatory T cells and regulates immune homeostasis. It also acts as a transcriptional repressor. Polyadenylation signal mutation of the gene leads to immune dysregulation, polyendocrinopathy, enteropathy and X-linked inheritance (IPEX). Abnormalities in the gene expression are also associated with the pathogenesis of autism spectrum disorders (ASD) and unexplained recurrent spontaneous abortion (URSA).
Physical form【外形】
Ascitic fluid containing 0.03% sodium azide.
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
mouse
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
ascites fluid
antibody product type
primary antibodies
clone【克隆】
2A11G9, monoclonal
species reactivity
mouse, human
technique(s)
direct ELISA: 1:10,000
immunohistochemistry: 1:200-1:1,000
indirect immunofluorescence: 1:200-1:1,000
western blot: 1:500-1:2,000
isotype【同位素/亚型】
IgG1
NCBI accession no.【NCBI登记号】
NM_014009
UniProt accession no.【UniProt登记号】
Q9BZS1
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... Foxp3(50943)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
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