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Monoclonal Anti-FDPS antibody produced in mouse

产品编号:3145003
规格:clone 3A6, purified immunoglobulin, buffered aqueous solution
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3145003100 μG4610
产品别名

Monoclonal Anti-FDPS antibody produced in mouse

FPPS

FPS

基本信息
NACRES
NA.41
General description【一般描述】
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene
Immunogen【免疫原】
FDPS (NP_001995.1, 320 a.a. ~ 419 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
VTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Features and Benefits【特点和优势】
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form【外形】
Solution in phosphate buffered saline, pH 7.4
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
mouse
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
purified immunoglobulin
antibody product type
primary antibodies
clone【克隆】
3A6, monoclonal
form【形式】
buffered aqueous solution
species reactivity
human
technique(s)
capture ELISA: suitable
isotype【同位素/亚型】
IgG2aκ
NCBI accession no.【NCBI登记号】
NM_002004
UniProt accession no.【UniProt登记号】
P14324
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... FDPS(2224)
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
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