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Monoclonal Anti-EXOSC4, (N-terminal) antibody produced in mouse
产品编号: | 3144794 |
规格: | clone 4F9, purified immunoglobulin, buffered aqueous solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Monoclonal Anti-EXOSC4, (N-terminal) antibody produced in mouse
RRP41A
p12A
RRP41
Rrp41p
hRrp41p
FLJ20591
SKI6
Ski6p
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | 4F9, monoclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | antigen ~37.11 kDa |
species reactivity | human |
technique(s) | capture ELISA: suitable indirect ELISA: suitable western blot: 1-5 μg/mL |
isotype【同位素/亚型】 | IgG2aκ |
NCBI accession no.【NCBI登记号】 | NM_019037 |
UniProt accession no.【UniProt登记号】 | Q9NPD3 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... EXOSC4(54512) |
基本信息
General description【一般描述】 | Mouse monoclonal antibody raised against a partial recombinant EXOSC4. The gene EXOSC4 (exosome component 4) is mapped to human chromosome 8q24.3. The encoded protein is present in the cytoplasm as well as nucleus and has a RNase pleckstrin homology (PH) domain. |
Immunogen【免疫原】 | EXOSC4 (NP_061910.1, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MAGLELLSDQGYRVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRGSRARALPDRALVNCQYSSATFSTGERKRRPHGDRKSCEMG |
Biochem/physiol Actions【生化/生理作用】 | EXOSC4 (exosome component 4) is a core component of the exosome complex and is required for the stability of the complex. The exosome complex exhibits 3′-5′ exoribonuclease function. EXOSC4 lacks ribonuclease activity but is involved in mRNA turnover. |
Physical form【外形】 | Solution in phosphate buffered saline, pH 7.4 |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 1 |