Monoclonal Anti-CD4 , (N-terminal) antibody produced in mouse

NA.41

CD4 (cluster of differentiation 4) molecule is encoded by the gene mapped to human chromosome 12p13.31. The encoded protein is mainly localized on the surface of specific leukocytes. CD4 is characterized with a four ecto-domains (D1-D4) of which D1, D2 and D4 contain disulfide bonds.

2 N-terminal domains of human CD4 fused to human IgG1 Fc

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 1 μg/mL of sample of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

CD4 (cluster of differentiation 4) facilitates the activation of immunostimulatory T-cells. It serves as a primary receptor for HIV-1 entry. The encoded protein also plays a key role in altering cell elasticity. Elevated expression of soluble CD4 has been observed in patients of infectious and chronic inflammatory diseases and rheumatoid arthritis (RA). Thus, this protein can be used as a potential diagnostic marker for the development of RA.

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Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

100

mouse

unconjugated

purified immunoglobulin

primary antibodies

MEM-241, monoclonal

buffered aqueous solution

human

1 mg/mL

flow cytometry: suitable

IgG1

NM_000616.4

P01730

wet ice

2-8℃

human ... CD4(920)

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12 - Non Combustible Liquids