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Monoclonal Anti-CD25 antibody produced in mouse
| 产品编号： | 3142526 |
| 规格： | clone 7G7B6, crude ascites, buffered aqueous solution |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Monoclonal Anti-CD25 antibody produced in mouse
TAC antigen
IL2RA
p55
CD_antigen=CD25
Interleukin-2 receptor subunit alpha
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | The CD25 gene, also referred to as IL2RA (interleukin 2 receptor subunit α), is mapped to human chromosome 10p15. The gene spans a length of 48 kb with eight exons. |
| Biochem/physiol Actions【生化/生理作用】 | The interleukin 2 receptor subunit α (IL2RA) gene encodes the α-chain of the IL-2 receptor complex. This receptor complex, made up of α, β, and a common γ chain, binds to its ligand, IL-2, which is a crucial growth factor for T- and B-cells. This ligand-receptor complex plays an important role in the regulation of immune responses. Variation in the chromosomal region containing this gene is associated with type 1 diabetes. This region is also linked to autoimmune thyroid disease indicating its role in autoimmunity. IL2RA has been found to confer a risk for multiple sclerosis. |
| Physical form【外形】 | Supplied in PBS with 0.09% (W/V) sodium azide |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | crude ascites |
| antibody product type | primary antibodies |
| clone【克隆】 | 7G7B6, monoclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 30819 Da |
| species reactivity | human |
| technique(s) | western blot: 1:100-~1:800 |
| isotype【同位素/亚型】 | IgG2a |
| NCBI accession no.【NCBI登记号】 | NP_000408.1 |
| UniProt accession no.【UniProt登记号】 | P01589 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... IL2RA(3559) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
