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Monoclonal Anti-CACNB1 antibody produced in mouse
产品编号: | 3142035 |
规格: | clone S7-18, 1 mg/mL, purified immunoglobulin |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Monoclonal Anti-CACNB1 antibody produced in mouse
Anti-Cavbeta1, S7-18
Anti-CACNB1
Anti-voltage dependent L type calcium channel beta 1 subunit
Anti-CACNLB1
Anti-CAB1
基本信息
NACRES | NA.41 |
General description【一般描述】 | The gene CACNB1 (calcium voltage-gated channel auxiliary subunit β 1) encodes a member of the calcium channel β subunit family. The gene spanning a length of 25kb contains 13 exons and is mapped to human chromosome 17. Alternative splicing at exons 7 and 13 produces β1a,β1b and βlc isoforms. |
Specificity【特异性】 | Detects ~80, 55 kDa. No cross-reactivity against Cav Beta4 |
Immunogen【免疫原】 | Synthetic peptide amino acids 19-34 of rat CavB1, Accession Number NP_059042 |
Biochem/physiol Actions【生化/生理作用】 | The gene CACNB1 (calcium voltage-gated channel auxiliary subunit β 1) encodes the human brain β1 subunit of voltage dependent calcium channels called dihydropyridine receptors (DHPR). They detect changes in membrane voltage by activating ryanodine receptors to release Ca2+ from the sarcoplasmic reticulum into the cytosol, leading to excitation–contraction (EC) coupling. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | S7-18, monoclonal |
form【形式】 | buffered aqueous glycerol solution |
mol wt【分子量】 | antigen predicted mol wt 55 kDa antigen predicted mol wt 80 kDa |
species reactivity | human, rat, mouse |
concentration【浓度】 | 1 mg/mL |
technique(s) | immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable |
isotype【同位素/亚型】 | IgG1 |
NCBI accession no.【NCBI登记号】 | NP_059042 |
UniProt accession no.【UniProt登记号】 | Q02641 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | rat ... Cacnb1(50688) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |