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Monoclonal Anti-BMP7 antibody produced in mouse

产品编号:3141734
规格:clone 1H3, purified immunoglobulin, buffered aqueous solution
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3141734100 μG5040
产品别名

Monoclonal Anti-BMP7 antibody produced in mouse

OP-1

基本信息
NACRES
NA.41
General description【一般描述】
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. (provided by RefSeq)
Immunogen【免疫原】
BMP7 (NP_001710, 293 a.a. ~ 390 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
STGSKQRSQNRSKTPKNQEALRMANVAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPET
Biochem/physiol Actions【生化/生理作用】
As implied by their name, bone morphogenetic proteins (BMPs) promote and regulate bone development and growth. BMP-7 induces apoptosis in B-cells. It has a role in organ development and may have a role in liver regeneration. Mutations in the gene encoding the protein have been shown to affect the development of teeth, palate and other orofacial complexes.
Physical form【外形】
Solution in phosphate buffered saline, pH 7.4
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
mouse
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
purified immunoglobulin
antibody product type
primary antibodies
clone【克隆】
1H3, monoclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
antigen 36.41 kDa
species reactivity
human
technique(s)
indirect ELISA: suitable
isotype【同位素/亚型】
IgG2aκ
NCBI accession no.【NCBI登记号】
NM_001719
UniProt accession no.【UniProt登记号】
P18075
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... BMP7(655)
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 3
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