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Monoclonal Anti-α1-Acid Glycoprotein antibody produced in mouse
基本信息
| MDL number | MFCD00162118 |
| NACRES | NA.41 |
| General description【一般描述】 | Monoclonal Anti-α1-Acid Glycoprotein (mouse IgG1 isotype) is derived from the AGP-47 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice. α1-Acid Glycoprotein (AGP) is an acute-phase plasma protein. This protein is mainly produced in the hepatocytes. AGP1 gene is mapped on the human chromosome at 9q32. |
| Specificity【特异性】 | Recognizes an epitope located on the 44 kDa subunit of denatured-reduced AGP using the immunoblotting technique. It does not cross react with human serum amyloid P component, human haptoglobin, human C-reactive protein, and human IgG. |
| Immunogen【免疫原】 | human α1-acid glycoprotein (AGP). |
| Biochem/physiol Actions【生化/生理作用】 | α1-Acid Glycoprotein (AGP) associates with haptoglobin and C-reactive protein, which indicates inflammation. Higher levels of AGP is associated with various inflammatory diseases, trauma, malignancies, myocardial infarction, rheumatoid arthritis, after major surgery, and in cases of chronic pain. This protein is capable of binding and transporting basic and neutral drugs. |
| Physical form【外形】 | The product is provided as ascites fluid with 0.1% sodium azide as a preservative. |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | ascites fluid |
| antibody product type | primary antibodies |
| clone【克隆】 | AGP-47, monoclonal |
| contains【包含】 | 15 mM sodium azide |
| species reactivity | human, baboon (weakly) |
| should not react with | canine, bovine |
| technique(s) | dot blot: suitable indirect ELISA: suitable western blot: 1:10,000 |
| isotype【同位素/亚型】 | IgG1 |
| UniProt accession no.【UniProt登记号】 | P02763 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... ORM1(5004) |
产品说明
| Storage and Stability【储存及稳定性】 | For continuous use, store at 2-8 ℃ for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
