您的位置：首页 > 产品中心 > Methyl-3,4-dephostatin
Methyl-3,4-dephostatin
产品别名
Methyl-3,4-dephostatin
3,4-Dihydroxy-N-methyl-N-nitrosoaniline
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C7H8N2O3 |
| Molecular weight | 168.15 |
| MDL number | MFCD01076450 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278575 |
| NACRES | NA.77 |
| Application【应用】 | Methyl-3,4-dephostatin has been used as:
|
| Biochem/physiol Actions【生化/生理作用】 | Methyl-3,4-dephostatin is a tyrphostin-related compound isolated from Streptomyces MJ742-NF5 strain. It favors nerve growth factor-based neurite formation in pheochromocytoma PC12 cells. Being a stable analog of the nitrosoaniline dephostatin, it can mimic phosphotyrosine substrate for Tyrosyl-DNA phosphodiesterase I (TdpI). Stable analog of dephostatin; selective protein tyrosine phosphatase 1B and SHPTP-1 inhibitor; does not inhibit CD45-associated phosphatases. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | >98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | red-brown |
| solubility【溶解性】 | DMSO: soluble 18 mg/mL H2O: insoluble |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CN(N=O)c1ccc(O)c(O)c1 |
| InChI | 1S/C7H8N2O3/c1-9(8-12)5-2-3-6(10)7(11)4-5/h2-4,10-11H,1H3 |
| InChI key | XAKAQCMEMMZUEO-UHFFFAOYSA-N |
| Gene Information | human ... PTPN1(5770) |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
