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Lipoprotein Lipase from Burkholderia sp.

产品编号:3105705
规格:lyophilized powder, ≥50,000 units/mg solid
CAS NO:9004-02-8
包装规格:10 MG,50 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
310570510 MG3220
310570550 MG11700
产品别名

9004-02-8

Lipoprotein Lipase from Burkholderia sp.

Diacylglycerol lipase

Diacylglycerol acylhydrolase

Lipoprotein Lipase from Pseudomonas sp.

基本信息
Enzyme Commission (EC) Number【酶学委员会(EC)编号】
3.1.1.34 ( BRENDA | IUBMB )
EC number【EC 号】
232-669-1
MDL number
MFCD00131523
NACRES
NA.54
General description【一般描述】
Lipoprotein Lipase (LPL) is a glycerol ester hydrolase. Several bacteria that produce LPL, belongs to the genus Pseudomonas, Serratia and Mucor.
Lipoprotein lipase hydrolyzes triglycerides in plasma lipoproteins causing release of fatty acids for metabolic purposes in muscles and adipose tissue.
Application【应用】
Lipoprotein Lipase from Burkholderia sp. has been used in the subcellular fractionation of mussel Mytilus galloprovincialis to identify the biomolecule attached to cytosolic fraction of okodaic acid. It has also been used to test its effect on serum amyloid A induced granulocyte colony-stimulated factor (G-CSF) expression in response to bacterial lipoprotein.
Lipoprotein lipase has been used in a study to assess the role of lipogenic enzymes in colorectal cancer. It has also been used in a study to investigate lipasemic activity of low molecular weight heparin in rats.
Biochem/physiol Actions【生化/生理作用】
Lipoprotein Lipase (LPL) hydrolysis triacylglycerol moieties in chylomicron and low density lipoproteins. LPL attaches lipoprotein to the vessel wall and facilitates their uptake. Abnormalities in LPL is associated with Alzheimer′s disease, atherosclerosis, obesity and chylomicronaemia.
Due to its lipolytic activity, lipoprotein lipase was shown to effectively block the spread of hepatitis C virus into healthy cells.
Lipoprotein lipase belongs to the family of triglyceride lipases. It hydrolyses triglycerides in triglyceride-rich ApoB-containing lipoproteins.
Unit Definition【单位定义】
One unit will release 1.0 nmole of p-nitrophenol per min at pH 7.2 at 37 ℃ using p-nitrophenyl butyrate as substrate.
产品性质
form【形式】
lyophilized powder
Quality Level【质量水平】
200
Specific Activity
≥50,000 units/mg solid
storage temp.【储存温度】
−20℃
packaging【包装】
10 mg in glass bottle
50 mg in poly bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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