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亮肽素 三氟乙酸盐
Leupeptin trifluoroacetate salt
| 产品编号： | 3105332 |
| 规格： | ≥90% (HPLC), microbial |
| CAS NO： | 147385-61-3 |
| 包装规格： | 1 MG，5 MG，10 MG，25 MG，50 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3105332 | 1 MG | 444 | |||
| 3105332 | 5 MG | 1710 | |||
| 3105332 | 10 MG | 2920 | |||
| 3105332 | 25 MG | 4870 | |||
| 3105332 | 50 MG | 8530 |
产品别名
147385-61-3
亮肽素 三氟乙酸盐
Leupeptin trifluoroacetate salt
Acetyl-Leu-Leu-Arg-al trifluoroacetate salt
Acetyl-Leu-Leu-Arg-al 三氟乙酸盐
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H38N6O4 · xC2HF3O2 |
| Molecular weight | 426.55 (free base basis) |
| MDL number | MFCD00133458 |
| PubChem Substance ID【PubChem化学物质编号】 | 329817397 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Inhibitor of serine and cysteine proteases. Inhibits plasmin, trypsin, papain, calpain, and cathepsin B. Does not inhibit pepsin, cathepsins A and D, thrombin, or α-chymotrypsin. Effective concentration 10-100 μM. There have been numerous studies using leupeptin to protect against hearing loss caused by acoustic overstimulation or the ototoxic antibiotic gentamicin. (Loss of cochlear hair cells is believed to be mediated by calpain.) |
| Analysis Note【分析说明】 | 由于三种形式在溶液中达到平衡，亮抑酶肽可在 HPLC 上形成多个峰。通过三个主峰测定纯度。主要的杂质肽为外消旋亮抑酶肽。 |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | microbial |
| Assay【测定】 | ≥90% (HPLC) |
| form【形式】 | powder |
| solubility【溶解性】 | H2O: 10 mM (Solutions are stable only a few hours. Stock solutions are stable up to 6 months at −20 ℃.) |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | OC(=O)C(F)(F)F.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C=O |
| InChI | 1S/C20H38N6O4.C2HF3O2/c1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22;3-2(4,5)1(6)7/h11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23);(H,6,7)/t15-,16-,17-;/m0./s1 |
| InChI key | WUHGBZVQELGOMH-FRKSIBALSA-N |
| packaging【包装】 | 5, 10, 25, 50, 100 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
