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LAG-3 (mouse): FC (mouse)

产品编号:3104274
规格:recombinant, expressed in CHO cells, >95% (SDS-PAGE)
包装规格:50 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
310427450 μG7110
产品别名

LAG-3 (mouse): FC (mouse)

ACEH

Lymphocyte activation gene-3

FDC protein

基本信息
NACRES
NA.32
General description【一般描述】
Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
Physical form【外形】
Solution in PBS.
Other Notes【其他说明】
The sequence coding for the 4 extracellular Ig-like domains of mouse LAG-3 (D1-D4) is fused to the Fc portion of mouse IgG2a (hinge-CH2-CH3).
产品性质
biological source【生物来源】
mouse
recombinant【重组】
expressed in CHO cells
Assay【测定】
>95% (SDS-PAGE)
form【形式】
liquid
mol wt【分子量】
monomer ~180 kDa by SDS-PAGE (non-reducing)
monomer ~80 kDa by SDS-PAGE (reducing)
packaging【包装】
pkg of 50 μg
storage condition【储存条件】
avoid repeated freeze/thaw cycles
concentration【浓度】
≥0.2 mg/mL
impurities【杂质】
<1 EU/μg endotoxin, tested
color【颜色】
clear
UniProt accession no.【UniProt登记号】
Q61790
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
mouse ... Lag3(16768)
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
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