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LAG-3 (mouse): FC (mouse)
产品编号: | 3104274 |
规格: | recombinant, expressed in CHO cells, >95% (SDS-PAGE) |
包装规格: | 50 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
LAG-3 (mouse): FC (mouse)
ACEH
Lymphocyte activation gene-3
FDC protein
基本信息
NACRES | NA.32 |
General description【一般描述】 | Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4. |
Physical form【外形】 | Solution in PBS. |
Other Notes【其他说明】 | The sequence coding for the 4 extracellular Ig-like domains of mouse LAG-3 (D1-D4) is fused to the Fc portion of mouse IgG2a (hinge-CH2-CH3). |
产品性质
biological source【生物来源】 | mouse |
recombinant【重组】 | expressed in CHO cells |
Assay【测定】 | >95% (SDS-PAGE) |
form【形式】 | liquid |
mol wt【分子量】 | monomer ~180 kDa by SDS-PAGE (non-reducing) monomer ~80 kDa by SDS-PAGE (reducing) |
packaging【包装】 | pkg of 50 μg |
storage condition【储存条件】 | avoid repeated freeze/thaw cycles |
concentration【浓度】 | ≥0.2 mg/mL |
impurities【杂质】 | <1 EU/μg endotoxin, tested |
color【颜色】 | clear |
UniProt accession no.【UniProt登记号】 | Q61790 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | mouse ... Lag3(16768) |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |