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吲哚美辛
Indomethacin
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| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3099516 | 500 MG | 1790 |
产品别名
53-86-1
吲哚美辛
Indomethacin
IDM
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic Acid
1-(4-氯苯甲酰基)-5-甲氧基-2-甲基-3-吲哚乙酸
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H16ClNO4 |
| Molecular weight | 357.79 |
| Beilstein | 497341 |
| EC number【EC 号】 | 200-186-5 |
| MDL number | MFCD00057095 |
| PubChem Substance ID【PubChem化学物质编号】 | 329823251 |
| NACRES | NA.24 |
| General description【一般描述】 | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Indomethacin drug is extensively employed as a pharmacologic agent to bring about the closure of patent ductus arteriosus (PDA) in premature infants. |
| Application【应用】 | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Indomethacin may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and plasma samples by chromatography techniques. |
| Biochem/physiol Actions【生化/生理作用】 | 环加氧酶 (COX) 抑制剂，对 COX-1 的选择性相对较高。 |
| Analysis Note【分析说明】 | These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
| Other Notes【其他说明】 | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Footnote【附注】 | To see an example of a Certificate of Analysis for this material enter LRAC0281 in the slot below. This is an example certificate only and may not be the lot that you receive. |
产品性质
| Quality Level【质量水平】 | 300 |
| grade【等级】 | certified reference material pharmaceutical secondary standard |
| CofA | current certificate can be downloaded |
| technique(s) | HPLC: suitable gas chromatography (GC): suitable |
| application(s) | pharmaceutical (small molecule) |
| format【格式】 | neat |
| pharmacopeia traceability【药典可追溯性】 | traceable to PhEur I0200000 traceable to USP 1341001 |
| storage temp.【储存温度】 | 2-30℃ |
| SMILES string | COc1ccc2n(c(C)c(CC(O)=O)c2c1)C(=O)c3ccc(Cl)cc3 |
| InChI | 1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) |
| InChI key | CGIGDMFJXJATDK-UHFFFAOYSA-N |
| Gene Information | human ... PTGS1(5742), PTGS2(5743) |
安全信息
| Pictograms【象形图】 | GHS06 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H300 |
| Precautionary Statements | P264 - P301 + P310 |
| Hazard Classifications【危险分类】 | Acute Tox. 1 Oral |
| Storage Class Code【储存分类代码】 | 6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials |
| WGK | WGK 3 |
