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IL-36β mouse
| 产品编号： | 3098336 |
| 规格： | recombinant, expressed in E. coli, untagged, >95% (SDS-PAGE) |
| 包装规格： | 10 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
IL-36β mouse
Interleukin-1 family member 8
Sentrin-specific protease 2
Interleukin-36β
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | IL-36α (IL-1F6), IL-36β (IL-1F8) and IL-36γ (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1β, IL-6, TNF-α and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination. |
| Physical form【外形】 | Lyophilized from PBS and 0.5% trehalose. |
| Reconstitution【重悬】 | Reconstitute with 100 μL deionized water. |
| Other Notes【其他说明】 | IL-36beta (mouse) (aa 31-183) is untagged. |
产品性质
| biological source【生物来源】 | mouse |
| recombinant【重组】 | expressed in E. coli |
| conjugate【偶联物】 | untagged |
| Assay【测定】 | >95% (SDS-PAGE) |
| form【形式】 | lyophilized |
| mol wt【分子量】 | ~17 kDa |
| packaging【包装】 | pkg of 10 μg |
| impurities【杂质】 | <0.01 EU/μg endotoxin, tested |
| color【颜色】 | white |
| UniProt accession no.【UniProt登记号】 | Q9D6Z6 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... Il36b(69677) |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
