您的位置：首页 > 产品中心 > 1553-60-2， Ibufenac
Ibufenac
产品别名
1553-60-2
Ibufenac
4-(2-Methylpropyl)-benzeneacetic acid
4-Isobutylphenylacetic acid
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C12H16O2 |
| Molecular weight | 192.25 |
| EC number【EC 号】 | 216-302-2 |
| MDL number | MFCD00864374 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825891 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Ibufenac is a non-steroidal anti-inflammatory drug (NSAID) analog of ibuprofen that was withdrawn for hepatotoxicity. It inhibits cyclooxygenases COX-1 and -2 activity with IC50 values of 17.4 and 13.1 μM, respectively and > 40 μM for 5-LOX. It has been used in studies of drug-induced hepatotoxicity. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 20 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | OC(CC1=CC=C(CC(C)C)C=C1)=O |
| InChI | 1S/C12H16O2/c1-9(2)7-10-3-5-11(6-4-10)8-12(13)14/h3-6,9H,7-8H2,1-2H3,(H,13,14) |
| InChI key | CYWFCPPBTWOZSF-UHFFFAOYSA-N |
| Gene Information | human ... PTGS1(5742), PTGS2(5743) |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
