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卤培米特
Halopemide
产品别名
59831-65-1
卤培米特
Halopemide
N-(2-(4-(5-Chloro-2-oxo-1-benzimidazolinyl)piperidino)ethyl)-p-fluorobenzamide
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C21H22ClFN4O2 |
Molecular weight | 416.88 |
MDL number | MFCD00866684 |
PubChem Substance ID【PubChem化学物质编号】 | 329815189 |
NACRES | NA.77 |
Application【应用】 | Halopemide, a non-specific phospholipase D (PLD) antagonist, may be used with selective PLD antagonists (CAY10593, a PLD1 antagonist; CAY10594 or ML298, selective PLD2 antagonist) to help define the role and physiological effects regulated by phospholipase D enzymes. Halopemide may be used as the basis of the design and development of more selective PLD antagonists. |
Biochem/physiol Actions【生化/生理作用】 | Halopemide is a dopamine receptor antagonist and a phospholipase D2 inhibitor. Halopemide may be used as a screen to identify inhibitors of human PLD2 using an in vitro biochemical assay. It is also inhibitory at benzodiazepine binding sites. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | off-white |
solubility【溶解性】 | DMSO: >10 mg/mL |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | Fc1ccc(cc1)C(=O)NCCN2CCC(CC2)N3C(=O)Nc4cc(Cl)ccc34 |
InChI | 1S/C21H22ClFN4O2/c22-15-3-6-19-18(13-15)25-21(29)27(19)17-7-10-26(11-8-17)12-9-24-20(28)14-1-4-16(23)5-2-14/h1-6,13,17H,7-12H2,(H,24,28)(H,25,29) |
InChI key | NBHPRWLFLUBAIE-UHFFFAOYSA-N |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Pictograms【象形图】 | GHS07 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H302 |
Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |