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Guanfacine Hydrochloride
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3094099 | 10 MG | 747 | |||
| 3094099 | 50 MG | 3110 |
产品别名
29110-48-3
Guanfacine Hydrochloride
N (Aminoiminomethyl)-2,6-dichlorobenzeneacetamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C9H9Cl2N3O · HCl |
| Molecular weight | 282.55 |
| MDL number | MFCD00798230 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278452 |
| NACRES | NA.77 |
| Application【应用】 | Guanfacine hydrochloride has been used as an α2A adrenoceptor agonist to test its protective effect on hypobaric hypoxia (HH) and in rat brain to measure blood oxygenation level dependent (BOLD) response. |
| Biochem/physiol Actions【生化/生理作用】 | Guanfacine stimulates the brain postsynaptic α2 adrenergic receptor (AR) and mediates the prefrontal cortical (PFC) neuronal regulation and strengthens their network. Guanfacine improves the density of neuronal dendrites and is useful in treating neuropsychiatric disorders. It modulates the synaptic and cytoskeletal proteins expression in prefrontal cortical (PFC) neurons and may improve hypobaric hypoxia (HH) induced PFC dysfunctions. Guanfacine enhances cognitive function and is recommended for attention deficit hyperactivity disorder (ADHD) therapy. α-2 noradrenergic receptor agonist. |
| Features and Benefits【特点和优势】 | This compound was developed by Promius. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| color【颜色】 | white |
| solubility【溶解性】 | H2O: soluble 12 mg/mL at 60 ℃ |
| originator【创始人】 | Promius |
| SMILES string | Cl.NC(=N)NC(=O)Cc1c(Cl)cccc1Cl |
| InChI | 1S/C9H9Cl2N3O.ClH/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13;/h1-3H,4H2,(H4,12,13,14,15);1H |
| InChI key | DGFYECXYGUIODH-UHFFFAOYSA-N |
| Gene Information | human ... ADRA2A(150), ADRA2B(151), ADRA2C(152) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
