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Goat anti-RENT1 Antibody, Affinity Purified
产品别名
Goat anti-RENT1 Antibody, Affinity Purified
pNORF1
RENT1
smg-2 homolog
KIAA0221
nonsense mediated mRNA decay factor (C. elegans)
UP Frameshift 1
smg-2
ATP-dependent helicase RENT1
Up-frameshift suppressor 1 homolog
NORF1
UPF1 regulator of nonsense transcripts homolog
delta helicase
HUPF1
Regulator of nonsense transcripts 1
Nonsense mRNA reducing factor 1
UPF1 regulator of nonsense transcripts homolog (yeast)
up-frameshift mutation 1 homolog
yeast Upf1p homolog
nonsense mediated mRNA decay factor
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | goat |
antibody form【抗体形式】 | affinity purified immunoglobulin |
antibody product type | primary antibodies |
grade【等级】 | Powered by Bethyl Laboratories, Inc. |
species reactivity | mouse, human |
concentration【浓度】 | 1 mg/mL |
technique(s) | immunoprecipitation (IP): 2-10 μg/mL western blot: 1:2,000-1:10000 |
accession no.【登记号】 | NP_002902.2 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | 2-8℃ |
Gene Information | goat ... UPF1(5976) |
基本信息
Immunogen【免疫原】 | The epitope recognized by PLA0010 maps to a region between residue 1075 and the C-terminus (residue 1118) of human Regulator of Nonsense Transcripts 1 (up-frameshift mutation 1 homolog) using the numbering given in entry NP_002902.2 (GeneID 5976). |
Physical form【外形】 | Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide |
Other Notes【其他说明】 | RENT1, also known as UPF1, is a key regulator of the nonsense-mediated mRNA decay (NMD) pathway. The NMD pathway eliminates mRNAs that prematurely terminate during translation and may serve to protect the cells from dominant-negative effects of truncated proteins, or as a means to regulate protein expression. RENT1 is an ATP-dependent 5′- 3′ RNA helicase and ATPase that localizes to the cytoplasm and is part of a post-splicing multiprotein complex as well as an mRNA decay complex. |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |