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Goat anti-DBC1/p30 DBC Antibody, Affinity Purified
产品别名
Goat anti-DBC1/p30 DBC Antibody, Affinity Purified
DBIRD complex subunit KIAA1967
KIAA1967
p30DBC
deleted in breast cancer 1
Deleted in breast cancer gene 1 protein
Cell division cycle and apoptosis regulator protein 2
DBC-1
p30 DBC protein
DBC.1
DBC1
NET35
deleted in breast cancer
p30 DBC
基本信息
NACRES | NA.41 |
Immunogen【免疫原】 | The epitope recognized by PLA0305 maps to a region between residue 873 to 923 of human p30 DBC Protein using the numbering given in entry NP_066997.3 (GeneID 57805). |
Physical form【外形】 | Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide |
Other Notes【其他说明】 | The DBC1 (Deleted in Breast Cancer Gene 1 protein) gene is located in a region frequently deleted in breast cancers. In its uncleaved form, DBC1 is localized to the nucleus. Upon cleavage by caspase activity, DBC1 becomes localized to the cytoplasm and functions to promote apoptosis. DBC1 has also been found to bind directly to the estrogen receptor alpha (ERalpha) hormone binding domain to modulate ERalpha expression and mediate hormone-independent breast cancer cell survival. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | goat |
antibody form【抗体形式】 | affinity purified immunoglobulin |
antibody product type | primary antibodies |
grade【等级】 | Powered by Bethyl Laboratories, Inc. |
species reactivity | human, mouse |
concentration【浓度】 | 1 mg/mL |
technique(s) | immunohistochemistry: 1:2,000-1:5,000 immunoprecipitation (IP): 2- 10 μg/mg western blot: 1:2,000-1:10,000 |
accession no.【登记号】 | NP_066997.3 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | 2-8℃ |
Gene Information | human ... CCAR2(57805) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |