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Fmoc-Asn(Trt)-OH

产品编号:3088617
规格:≥97.0%
CAS NO:132388-59-1
包装规格:5 G,25 G,100 G,1 KG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
30886175 G733
308861725 G1330
3088617100 G2250
30886171 KG15420
产品别名

132388-59-1

Fmoc-Asn(Trt)-OH

Nα-(9-Fluorenylmethoxycarbonyl)-Nγ-trityl-L-asparagine

Nα-Fmoc-Nγ-trityl-L-asparagine

Nα-(9-芴甲氧羰基)-Nγ-三苯甲基-L-天冬酰胺

Nα-Fmoc-Nγ-三苯甲基-L-天冬酰胺

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C38H32N2O5
Molecular weight
596.67
Beilstein
4343823
MDL number
MFCD00077049
eCl@ss
32160406
PubChem Substance ID【PubChem化学物质编号】
57651076
NACRES
NA.26
General description【一般描述】
Fmoc-Asn(Trt)-OH has good solubility properties in most organic solvents, and its use has been shown to result in significantly purer peptides than other derivatives used for the introduction of Asn [1, 2]. Coupling can be performed by standard procedures. The trityl group is normally removed by 95% TFA in 1-3 hours, with no alkylation of Trp residues. When Asn(Trt) is the N-terminal residue, the reaction time may need to be extended to ensure complete deprotection [3].
Application【应用】
Fmoc-Asn(Trt)-OH has been used to synthesize peptides on cellulose membrane by SPOT method
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥97.0%
optical activity【旋光性】
[α]20/D −15.0±1°, c = 1% in methanol
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
mp
201-204 ℃ (lit.)
application(s)
peptide synthesis
functional group【官能团】
Fmoc
storage temp.【储存温度】
2-8℃
SMILES string
OC(=O)[C@H](CC(=O)NC(c1ccccc1)(c2ccccc2)c3ccccc3)NC(=O)OCC4c5ccccc5-c6ccccc46
InChI
1S/C38H32N2O5/c41-35(40-38(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28)24-34(36(42)43)39-37(44)45-25-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33/h1-23,33-34H,24-25H2,(H,39,44)(H,40,41)(H,42,43)/t34-/m0/s1
InChI key
KJYAFJQCGPUXJY-UMSFTDKQSA-N
packaging【包装】
5, 25, 100 g in poly bottle
1 kg in poly bottle
安全信息
Pictograms【象形图】
GHS09
Hazard Statements
H411
Hazard Classifications【危险分类】
Aquatic Chronic 2
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 2
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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