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Exo2
产品别名
304684-77-3
Exo2
2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C18H18N4O2S |
| Molecular weight | 354.43 |
| MDL number | MFCD00380179 |
| PubChem Substance ID【PubChem化学物质编号】 | 329799006 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Exo2 acts as a chemical probe of intracellular transport. Edxo2 has activities similar to Brefeldin A with membrane trafficking to the Golgi appartus, but appears more selective. Exo2 is a bioactive small molecule that activates Golgi-endoplasmic reticulum (ER) fusion in mammals by distorting the Golgi apparatus. It prevents the release of secretory cargo from the ER. Exo2 do not modify the morphology of the trans-Golgi network (TGN). It also inhibits the anterograde movement of vesicular stomatitis virus G (VSV G) glycoprotein, from ER to Golgi. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | yellow |
| solubility【溶解性】 | DMSO: >20 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | COc1cc(ccc1O)\C=N\Nc2ncnc3sc4CCCCc4c23 |
| InChI | 1S/C18H18N4O2S/c1-24-14-8-11(6-7-13(14)23)9-21-22-17-16-12-4-2-3-5-15(12)25-18(16)20-10-19-17/h6-10,23H,2-5H2,1H3,(H,19,20,22)/b21-9+ |
| InChI key | VFNUTEMVQGLDAG-ZVBGSRNCSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
