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EUK-8
产品别名
53177-12-1
EUK-8
(Salen)manganese(III) chloride
Chloro(bis(salicylidene)ethylenediamine)manganese
Manganese(salen) chloride
Chloro[N,N′-ethylenebis(salicylideneaminato)]manganese
EUK 8
(SP-5-13)-Chloro[[2,2′-[1,2-ethanediylbis(nitrilomethylidyne)]bis[phenolato]](2-)-N,N′,O,O′]-manganese
基本信息
Empirical Formula【经验(实验)分子式】 | C16H14ClMnN2O2 |
Molecular weight | 356.69 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | EUK-8 is a salen manganese complex that exhibit potent antioxidant activities. EUK-8 is a superoxide dismutase (SOD) that inhibits amyloid fibril formation, including islet amyloid polypeptide (IAPP), β-amyloid and lysozyme amyloid aggregation. It appears that EUK-8 disrupts the pre-formed amyloid fibrils. EUK-8 increases the viability of the SK-N-MC cells exposed to preformed IAPP fibrils. |
Other Notes【其他说明】 | air sensitive |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥95% (HPLC) |
form【形式】 | powder |
storage condition【储存条件】 | desiccated |
color【颜色】 | , faint to very dark brown |
solubility【溶解性】 | H2O: 1 mg/mL, clear |
storage temp.【储存温度】 | −20℃ |
InChI | 1S/C16H16N2O2.ClH.Mn/c19-15-7-3-1-5-13(15)11-17-9-10-18-12-14-6-2-4-8-16(14)20;;/h1-8,11-12,19-20H,9-10H2;1H;/q;;+3/p-3 |
InChI key | HBQGFROGWOHBAG-UHFFFAOYSA-K |
packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |