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DMT-dC(bz) Pharmadite®
产品别名
DMT-dC(bz) Pharmadite®
DMT-dC(bz) Phosphoramidite
N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxycytidine, 3′-[2-cyanoethyl N,N-?bis(1-methylethyl)phosphoramidite]
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C46H52N5O8P |
Molecular weight | 833.91 |
MDL number | MFCD00036315 |
PubChem Substance ID【PubChem化学物质编号】 | 329774847 |
NACRES | NA.51 |
Legal Information【法律信息】 | Pharmadite is a registered trademark of sigma-aldrich Co. LLC |
产品性质
Quality Level【质量水平】 | 200 |
biological source【生物来源】 | non-animal source (no BSE/TSE risk) |
type【类型】 | for DNA synthesis |
product line【产品线】 | Proligo Reagents |
Assay【测定】 | ≥99.5% (reversed phase HPLC) >99.5% (31P-NMR) conforms (1H-NMR) conforms (LC/MS) |
form【形式】 | powder or granules |
technique(s) | oligo synthesis: suitable |
impurities【杂质】 | >= 170ppm, none detected (S/N <2.5) ≤0.1% P(III) 100-169ppm (31P-NMR) ≤0.1% single unspecified Imprity (reversed phase HPLC) ≤0.3% dC2 (reversed phase HPLC, DMT-dC(bz) cyanoethyl-H-posphonate) ≤0.3% dC3 (reversed phase HPLC, DMT-dC(bz) phosphoramidate) ≤0.3% dC5 (reversed phase HPLC, O3′-Benzoyl-O5′-DMT-dC(bz)) ≤0.30 wt. % water content (Karl Fischer) ≤0.5% P(V) -25-99ppm (31P-NMR) ≤3.0 wt. % residual solvent content |
color【颜色】 | white to off-white |
solubility【溶解性】 | soluble, clear |
nucleoside profile【核苷分析】 | base: deoxycytidine base protecting group: benzoyl 2' protecting group: none 5' protecting group: DMT deprotection: standard |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C=CC(NC(=O)c4ccccc4)=NC3=O)(c5ccccc5)c6ccc(OC)cc6 |
InChI | 1S/C46H52N5O8P/c1-32(2)51(33(3)4)60(57-29-13-27-47)59-40-30-43(50-28-26-42(49-45(50)53)48-44(52)34-14-9-7-10-15-34)58-41(40)31-56-46(35-16-11-8-12-17-35,36-18-22-38(54-5)23-19-36)37-20-24-39(55-6)25-21-37/h7-12,14-26,28,32-33,40-41,43H,13,29-31H2,1-6H3,(H,48,49,52,53)/t40-,41+,43+,60?/m0/s1 |
InChI key | PGTNFMKLGRFZDX-SALLYJDFSA-N |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 1 |