DL-缬氨酸

CH₃CH₂CH₂CH(NH₂)COOH

117.15

1721163

212-082-7

MFCD00064420

24897829

NA.26

Norvaline is a non-proteinogenic α-amino acid and is also called DL-α-aminovaleric acid. It is produced in Gram-negative microorganisms including Escherichia coli and is also a part of the antifungal peptide produced by Bacillus subtilis.

DL-Norvaline has been used as an internal standard:

• to analyze metabolites in cultured mammalian cells by gas chromatography-mass spectrometry (GC-MS)
• to convert cysteine and cystine to Cys MPA (S-2-carboxyethylthio-L-cysteine) and quantify the same using a high-performance liquid chromatography (HPLC) analyzer
• for free amino acid analysis in samples of oocytes by liquid chromatography

Norvaline mediates physiological and pathophysiological processes promoting nitric oxide production. It is used to treat Alzheimer′s disease and is effective against artificial metabolic syndrome in rats. Norvaline exhibits phase transition upon cooling below 190 K and hence it is useful in molecular machines. DL-Norvaline serves as a prototype for research in polymorphism and molecular dynamics of aliphatic α-amino acids containing linear side-chain. It influences the activity, stability, and side-chain packaging of proteins.
DL-戊氨酸是一种神经递质。

≥98% (TLC)

200

powder

HPLC: suitable

white

>300 ℃

CCCC(N)C(O)=O

1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)

SNDPXSYFESPGGJ-UHFFFAOYSA-N

25, 100 g in poly bottle

13 - Non Combustible Solids

WGK 3

Eyeshields, Gloves, type N95 (US)