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Dienogest
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3076209 | 10 MG | 1220 | |||
3076209 | 50 MG | 4490 |
产品别名
65928-58-7
Dienogest
17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile
17-cyanomethyl-17-hydroxy-estra-4,9-dien-3-one
(17a)-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C20H25NO2 |
Molecular weight | 311.42 |
MDL number | MFCD00868356 |
PubChem Substance ID【PubChem化学物质编号】 | 329825902 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | Dienogest is used to treat endometriosis. It might also help to decrease the levels of plasma estradiol by stimulating cell death of granulosa cells in the ovary. Dienogest is a fourth-generation progestin, an orally active synthetic progestogen with approximately 10% of the relative affinity of progesterone, but has a very potent progestagenic effect in the endometrium with some antiandrogenic activity and without any androgenic, glucocorticoid or mineralocorticoid effects. It has been used alone or in combination as a contraceptive and to treat uterine fibroids. Dienogest inhibits ovulation primarily through peripheral action rather than by central action on gonadotrophin secretion. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
optical activity【旋光性】 | [α]/D -305 to -325°, c = 1 in dichloromethane |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 5 mg/mL, clear (warmed) |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | O[C@@]1(CC#N)CC[C@@]2([H])[C@]3([H])CCC4=CC(CCC4=C3CC[C@@]21C)=O |
InChI | 1S/C20H25NO2/c1-19-8-6-16-15-5-3-14(22)12-13(15)2-4-17(16)18(19)7-9-20(19,23)10-11-21/h12,17-18,23H,2-10H2,1H3/t17-,18+,19+,20-/m1/s1 |
InChI key | AZFLJNIPTRTECV-FUMNGEBKSA-N |
packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
Pictograms【象形图】 | GHS08 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H361 |
Precautionary Statements | P280 |
Hazard Classifications【危险分类】 | Repr. 2 |
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |