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Dienogest

产品编号:3076209
规格:≥98% (HPLC)
CAS NO:65928-58-7
包装规格:10 MG,50 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
307620910 MG1220
307620950 MG4490
产品别名

65928-58-7

Dienogest

17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile

17-cyanomethyl-17-hydroxy-estra-4,9-dien-3-one

(17a)-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C20H25NO2
Molecular weight
311.42
MDL number
MFCD00868356
PubChem Substance ID【PubChem化学物质编号】
329825902
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
Dienogest is used to treat endometriosis. It might also help to decrease the levels of plasma estradiol by stimulating cell death of granulosa cells in the ovary.
Dienogest is a fourth-generation progestin, an orally active synthetic progestogen with approximately 10% of the relative affinity of progesterone, but has a very potent progestagenic effect in the endometrium with some antiandrogenic activity and without any androgenic, glucocorticoid or mineralocorticoid effects. It has been used alone or in combination as a contraceptive and to treat uterine fibroids. Dienogest inhibits ovulation primarily through peripheral action rather than by central action on gonadotrophin secretion.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
optical activity【旋光性】
[α]/D -305 to -325°, c = 1 in dichloromethane
color【颜色】
white to beige
solubility【溶解性】
DMSO: 5 mg/mL, clear (warmed)
storage temp.【储存温度】
2-8℃
SMILES string
O[C@@]1(CC#N)CC[C@@]2([H])[C@]3([H])CCC4=CC(CCC4=C3CC[C@@]21C)=O
InChI
1S/C20H25NO2/c1-19-8-6-16-15-5-3-14(22)12-13(15)2-4-17(16)18(19)7-9-20(19,23)10-11-21/h12,17-18,23H,2-10H2,1H3/t17-,18+,19+,20-/m1/s1
InChI key
AZFLJNIPTRTECV-FUMNGEBKSA-N
packaging【包装】
10, 50 mg in glass bottle
安全信息
Pictograms【象形图】
GHS08
Signal word【警示用语:】
Warning
Hazard Statements
H361
Precautionary Statements
P280
Hazard Classifications【危险分类】
Repr. 2
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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