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芦荟大黄素
Diacerein impurity B
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| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3075498 | 1400 |
产品别名
481-72-1
芦荟大黄素
Diacerein impurity B
1,8-Dihydroxy 3-hydroxymethylanthraquinone
Rhabarberone
1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone
Aloe-emodin
3-Hydroxymethylchrysazine
1,8-二羟基-3-(羟甲基)蒽甲苯
3-羟甲基白杨嗪
弹力素
1,8-二羟基3-羟甲基蒽甲苯
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C15H10O5 |
| Molecular weight | 270.24 |
| Beilstein | 2059062 |
| MDL number | MFCD00017373 |
| PubChem Substance ID【PubChem化学物质编号】 | 329831502 |
| NACRES | NA.24 |
| General description【一般描述】 | Diacerein is known to be a suitable drug to treat osteoarthritis and prevent vascular diseases. It is a semi-synthetic anthraquinone derivative which acts by inhibiting the production of interleukin-1 and secretion of metalloproteases. This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia. |
| Biochem/physiol Actions【生化/生理作用】 | 复方泻药/泻药；通过释放内源性乙酰胆碱来增加肠道平滑肌的收缩。抗肿瘤活性与活性氧簇 (ROS) 产生增加相关，活性氧簇反过来降低线粒体跨膜电位，从而诱导渗透性转换，启动一系列事件，最终导致细胞凋亡。遗传毒性和致突变性似乎是由于芦荟大黄素抑制了拓扑异构酶II的活性。 |
| Caution【注意】 | Please find SDS provided by EDQM here.. |
| Other Notes【其他说明】 | Sales restrictions may apply. |
产品性质
| biological source【生物来源】 | synthetic |
| grade【等级】 | pharmaceutical primary standard |
| agency | EP |
| form【形式】 | solid |
| manufacturer/tradename | EDQM |
| technique(s) | gas chromatography (GC): suitable liquid chromatography (LC): suitable |
| application(s) | pharmaceutical (small molecule) |
| format【格式】 | neat |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | OCc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1 |
| InChI | 1S/C15H10O5/c16-6-7-4-9-13(11(18)5-7)15(20)12-8(14(9)19)2-1-3-10(12)17/h1-5,16-18H,6H2 |
| InChI key | YDQWDHRMZQUTBA-UHFFFAOYSA-N |
| packaging【包装】 | Unit quantity: 20 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue. |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
