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Desmosine chloride
| 产品编号： | 3075095 |
| 规格： | from bovine, 99.5%±0.2% |
| CAS NO： | 10019-68-8 |
| 包装规格： | 1 μMOL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
10019-68-8
Desmosine chloride
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C24H40ClN5O8 |
| Molecular weight | 562.06 |
| MDL number | MFCD12910449 |
| PubChem Substance ID【PubChem化学物质编号】 | 329798901 |
| NACRES | NA.56 |
| General description【一般描述】 | Each vial contains 1 μmole of purified desmosine. |
| Application【应用】 | Desmosine chloride is often used in assays for free or urinary desmosine as markers for disease states characterized by elastin degradation (e.g., emphysema). Elastin degradation has shown strong correlation with vascular calcification, and pretreatment with aluminum ions can inhibit the binding of matrix metalloproteinase (MMP) to elastin. Assays for free or urinary desmosine are often used as markers for disease states characterized by elastin degradation (e.g., emphysema). Conversely, excessive levels of incorporated desmosine are indicators of fibrotic conditions (e.g., cirrhosis). |
| Biochem/physiol Actions【生化/生理作用】 | Desmosine is a polyfunctional amino acid that forms cross-links in mature elastin. |
| Caution【注意】 | 极易吸湿 |
| Analysis Note【分析说明】 | Calibrated by UV and amino acid analysis. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | bovine |
| Assay【测定】 | 99.5%±0.2% |
| form【形式】 | lyophilized powder |
| purified by【纯化方式】 | chromatography (and purified by solvent extraction) |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | [Cl-].NC(CCCC[n+]1cc(CCC(N)C(O)=O)c(CCCC(N)C(O)=O)c(CCC(N)C(O)=O)c1)C(O)=O |
| InChI | 1S/C24H39N5O8.ClH/c25-17(21(30)31)5-1-2-11-29-12-14(7-9-19(27)23(34)35)16(4-3-6-18(26)22(32)33)15(13-29)8-10-20(28)24(36)37;/h12-13,17-20H,1-11,25-28H2,(H3-,30,31,32,33,34,35,36,37);1H |
| InChI key | FUPMLZCXPJSGPV-UHFFFAOYSA-N |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
