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地氯雷他定

Desloratadine
产品编号:3075087
规格:powder, ≥98% (HPLC)
CAS NO:100643-71-8
包装规格:10 MG,50 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
307508710 MG2710
307508750 MG9290
产品别名

100643-71-8

地氯雷他定

Desloratadine

8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H- benzo[5,6]cyclohepta[1,2,b]pyridine

Clarinex

NSC 675447

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C19H19ClN2
Molecular weight
310.82
MDL number
MFCD00871949
PubChem Substance ID【PubChem化学物质编号】
329798668
NACRES
NA.32
Application【应用】
Desloratadine has been used to test its effect on embryoid body development in in vitro gastrulation model of P19C5 stem cells. It has also been used as an antihistamine mimic in rats and to treat lung cancer (A549) and glioblastoma (U87) cells in various cellular studies.
Biochem/physiol Actions【生化/生理作用】
Desloratadine is a selective and nonsedating histamine H1 receptor antagonist, an active metabolite of loratadine (Claritin), used to relieve hay fever and allergy symptoms with less drowsiness than other antihistamines; does not significantly inhibits cardiac K+ channels at clinically achievable blood levels. Free from antimuscarinic/anticholinergic effects.
Other Notes【其他说明】
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. D1069.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Legal Information【法律信息】
Clarinex is a registered trademark of Schering Corp.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
solubility【溶解性】
DMSO: >10 mg/mL
storage temp.【储存温度】
2-8℃
SMILES string
Clc1ccc2c(CCc3cccnc3\C2=C4\CCNCC4)c1
InChI
1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2
InChI key
JAUOIFJMECXRGI-UHFFFAOYSA-N
Gene Information
human ... HRH1(3269)
packaging【包装】
10, 50 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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