广州伟伯科技有限公司
您的位置:首页 > 产品中心 > 209984-56-5, 脱羟基 LY-411575
产品搜索:

脱羟基 LY-411575

Deshydroxy LY-411575
产品编号:3075077
规格:≥98% (HPLC)
CAS NO:209984-56-5
包装规格:5 MG,25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
30750775 MG1550
307507725 MG4550
产品别名

209984-56-5

脱羟基 LY-411575

Deshydroxy LY-411575

Dibenzazepine

YO-01027

(S,S)-2-[2-(3,5-Difluorophenyl)acetylamino]-N-(5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)propionamide

GSI-XX

N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-benzeneacetamide

DBZ

γ-Secretase inhibitor XX

基本信息
Empirical Formula【经验(实验)分子式】
C26H23F2N3O3
Molecular weight
463.48
NACRES
NA.77
Application【应用】
Deshydroxy LY-411575 has been used in dibenzazepine (DBZ) treatment and chemical treatment.
Biochem/physiol Actions【生化/生理作用】
LY411575 prevents SPP (signal peptide peptidase) dependent cleavage of HCV (hepatitis C virus) core protein.
Deshydroxy LY-411575 is a cell-permeable γ-secretase inhibitor and inhibtor of Notch processing. Deshydroxy LY-411575 significantly lowers both brain and plasma Aβ40 levels by ~72% in Tg2576 mutant APP transgenic mouse model and potently blocks Notch processing, with an IC50 of 1.7 nM in SupT1 cells.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
white to beige
solubility【溶解性】
DMSO: 15 mg/mL, clear
storage temp.【储存温度】
−20℃
packaging【包装】
5, 25 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
广州伟伯科技有限公司 版权所有 CopyRight ©2006-2024, All Rights Reserved
工信部备案号:粤ICP备08114744号   Page Run Time: 0.0142