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脱氧胆酸
Deoxycholic Acid
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3074967 | 25 G | 749 | |||
3074967 | 100 G | 1720 |
产品别名
83-44-3
脱氧胆酸
Deoxycholic Acid
7-Deoxycholic acid
Desoxycholic acid
3α,12α-Dihydroxy-5β-cholanic acid
7-脱氧胆酸
3α,12α-二羟基-5β-胆汁酸
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C24H40O4 |
Molecular weight | 392.57 |
Beilstein | 3219882 |
EC number【EC 号】 | 201-478-5 |
MDL number | MFCD00003673 |
PubChem Substance ID【PubChem化学物质编号】 | 329753610 |
NACRES | NA.77 |
General description【一般描述】 | Deoxycholic acid is an amphiphilic molecule and an important constituent of bile acid. It contains hydroxyl groups substituted at the 3α and 12α positions and a carboxyl group towards the end of the branched-chain. These moieties contribute to the hydrophilic nature of the molecule and the hydrophobic cyclopentanophenanthrene forms its center. |
Application【应用】 | Deoxycholic acid has been used as:
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Biochem/physiol Actions【生化/生理作用】 | Deoxycholic acid, due to its amphiphilicity, significantly helps to solubilize, emulsify, and absorb fat, vitamins, and cholesterol in the body. High levels of intestinal deoxycholic acid might cause colorectal cancer by inducing oxidative stress and leading to DNA damage. It acts as an oncogene and pro-tumor factor. |
Other Notes【其他说明】 | 用于β-肾上腺素能受体的增溶 |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | ox bile |
description【描述】 | anionic |
Assay【测定】 | ≥99.0% (T) |
form【形式】 | powder |
optical activity【旋光性】 | [α]20/D +54±1°, c = 1% in ethanol |
mol wt【分子量】 | 392.57 g/mol |
impurities【杂质】 | ≤1% cholic acid (TLC) |
mp | 170-175 ℃ 171-174 ℃ (lit.) |
functional group【官能团】 | carboxylic acid |
SMILES string | C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C |
InChI | 1S/C24H40O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-/m1/s1 |
InChI key | KXGVEGMKQFWNSR-LLQZFEROSA-N |
Gene Information | human ... ATIC(471) |
安全信息
Pictograms【象形图】 | GHS07 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H302 |
Precautionary Statements | P301 + P312 + P330 |
Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |
Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |