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Decursin

产品编号:3074716
规格:≥97% (HPLC)
CAS NO:5928-25-6
包装规格:1 MG,5 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
30747161 MG1350
30747165 MG4000
产品别名

5928-25-6

Decursin

(+)-Decursin

(7S)-7,8-Dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b′]dipyran-7-yl 3-methyl-2-butenoate

3-Methyl-2-butenoic acid (7S)-7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-pyrano[3,2-g]-1-benzopyran-7-yl ester

基本信息
Empirical Formula【经验(实验)分子式】
C19H20O5
Molecular weight
328.36
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
Decursin is a cumarin isolated from Radix peucedani that exhibits a number of physiological actions including anticancer, antibacterial, antinematodal and antioxidant. Decursin is potent anti-angiogenic agent targeting the VEGFR-2 signaling pathway. Decursin exhibits potent neuroprotective activity against glutamate and Ab- induced neurotoxicity. Apparently, decursin stimulates activation of Nerf2. Also, decursin inhibits androgen stimulated AR translocation to the nucleus in LNCaP prostate cancer cells.
Features and Benefits【特点和优势】
This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
产品性质
biological source【生物来源】
Radix peucedani
Quality Level【质量水平】
100
Assay【测定】
≥97% (HPLC)
form【形式】
powder
optical activity【旋光性】
[α]/D +120 to +160°, c = 0.5 in chloroform-d
color【颜色】
white to beige
solubility【溶解性】
DMSO: 5 mg/mL, clear
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
InChI
1S/C19H20O5/c1-11(2)7-18(21)23-16-9-13-8-12-5-6-17(20)22-14(12)10-15(13)24-19(16,3)4/h5-8,10,16H,9H2,1-4H3/t16-/m0/s1
InChI key
CUKSFECWKQBVED-INIZCTEOSA-N
packaging【包装】
1, 5 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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