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DCHC
产品别名
302953-06-6
DCHC
3-(2,4-Dichlorophenyl)-7-hydroxy-4H-chromen-4-one
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C15H8Cl2O3 |
| Molecular weight | 307.13 |
| MDL number | MFCD01848896 |
| PubChem Substance ID【PubChem化学物质编号】 | 329798809 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | DCHC is a SIRT1 activator. It increases peroxisome proliferator-activated receptor gamma co-activator 1α (PGC1α) expression, resulting in mitochondrial biogenesis. DCHC activates SIRT1 at low micromolar concentrations (5–10 μM) and increases SIRT1 activity at 100 μM. It is different from 5,7,4′-T in that it induces the activation of recombinant SIRT1, but does not increase SIRT1 expression. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| color【颜色】 | yellow |
| solubility【溶解性】 | DMSO: >20 mg/mL |
| SMILES string | Oc1ccc2C(=O)C(=COc2c1)c3ccc(Cl)cc3Cl |
| InChI | 1S/C15H8Cl2O3/c16-8-1-3-10(13(17)5-8)12-7-20-14-6-9(18)2-4-11(14)15(12)19/h1-7,18H |
| InChI key | QMSGNLMBWFRALO-UHFFFAOYSA-N |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS06 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| Hazard Classifications【危险分类】 | Acute Tox. 3 Oral |
| Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
