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D4476

产品编号:3074397
规格:≥98% (HPLC), solid
CAS NO:301836-43-1
包装规格:1 MG,5 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
30743971 MG2300
30743975 MG8300
产品别名

301836-43-1

D4476

4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-2-yl-1H-imidazol-2-yl)benzamide

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C23H18N4O3
Molecular weight
398.41
PubChem Substance ID【PubChem化学物质编号】
329798715
NACRES
NA.77
Application【应用】
D4476 has been used as a casein kinase I inhibitor (CKI) in various experiments.
Biochem/physiol Actions【生化/生理作用】
D4476 may prevent or enhance apoptosis. It triggers tumor suppressor p53 and impairs transcription factor E2F-1.
D4476 is a potent, selective ATP-competitive inhibitor of CK1 (casein kinase 1).
Features and Benefits【特点和优势】
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
solid
color【颜色】
light yellow
solubility【溶解性】
DMSO: ~20 mg/mL
H2O: insoluble
originator【创始人】
GlaxoSmithKline
storage temp.【储存温度】
2-8℃
SMILES string
NC(=O)c1ccc(cc1)-c2nc(-c3ccccn3)c([nH]2)-c4ccc5OCCOc5c4
InChI
1S/C23H18N4O3/c24-22(28)14-4-6-15(7-5-14)23-26-20(21(27-23)17-3-1-2-10-25-17)16-8-9-18-19(13-16)30-12-11-29-18/h1-10,13H,11-12H2,(H2,24,28)(H,26,27)
InChI key
DPDZHVCKYBCJHW-UHFFFAOYSA-N
packaging【包装】
1, 5 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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