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CP-471474

产品编号:3072665
规格:≥98% (HPLC)
CAS NO:210755-45-6
包装规格:5 MG,25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
30726655 MG1370
307266525 MG4770
产品别名

210755-45-6

CP-471474

PF-1626077

2-[[[4-(4-Fluorophenoxy)phenyl]sulfonyl]amino]-N-hydrox y-2-methylpropanamide

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C16H17FN2O5S
Molecular weight
368.38
MDL number
MFCD16618408
PubChem Substance ID【PubChem化学物质编号】
329823722
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
CP-471474 is a broad spectrum inhibitor of matrix metalloproteinases. CP-471474 has a low nM IC50 efficacy for MMP-2, MMP-3, MMP-9, and MMP-13. CP-471474 has low potency against MMP-1 (IC50 > 1 uM). CP-471474 prevents left ventricular remodeling after experimental myocardial infarction in mice. CP-471474 also inhibits cigarette smoke-induced lung inflammation and the progression of emphysema in guinea pig models.
Other Notes【其他说明】
This compound was developed by Pfizer for Cytoskeleton & Extracellular Matrix research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Legal Information【法律信息】
Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
manufacturer/tradename
Pfizer®
color【颜色】
white to off-white
solubility【溶解性】
DMSO: ≥20 mg/mL
originator【创始人】
Pfizer
storage temp.【储存温度】
room temp
SMILES string
CC(C)(NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1)C(=O)NO
InChI
1S/C16H17FN2O5S/c1-16(2,15(20)18-21)19-25(22,23)14-9-7-13(8-10-14)24-12-5-3-11(17)4-6-12/h3-10,19,21H,1-2H3,(H,18,20)
InChI key
QCOQJYRPDUMCNP-UHFFFAOYSA-N
packaging【包装】
5, 25 mg in glass bottle
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H302
Hazard Classifications【危险分类】
Acute Tox. 4 Oral
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 1
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